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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Patient

Value Required

131568

Disease Body Location

Musculoskeletal

OS

10031291 - Osteosarcoma

Diagnosis Subtype

Date of Diagnosis

06/2009

Age at Diagnosis

31

NCI PDMR Models

Contributor PDX ID

Grade/Stage
Information Available

None Provided

Has Known
Metastatic Disease

Recurrent disease: dedifferentiation of prior parosteal osteosarcoma.

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Germline Whole Exome Sequence Files (if available)

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Limited Medical Information (provided after delinking)

Current Therapy

View	Date Regimen Started	Standardized Regimen	Best Response	Number of Cycles	Date of Progression or Off Therapy	Comments	Reason for Off Therapy
		No Current Therapy	NA	0

Prior Therapies and Response

View	Date Regimen Started	Standardized Regimen	Best Response	Duration Months	Comments
	02/2016	Cisplatin, Doxorubicin	Disease Progression	4	neoadjuvant for 3 cycles

Additional Patient History

Molecular
and
IHC Data

Additional
Medical
History

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Social History (provided after delinking)

Social History

View	Ethnicity	Race	Occupation	Has Smoked 100 Cigarettes	Total Pack Years	Tobacco Use History
	Not Provided	Black or African American	Human Resources	No	-	-

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Genetic Ancestry (SNPweights)

View	Source Sequence	%European (CEU)	%East Asian (EA)	%Native and Latin American (NA)	%West African (YRI)	Inferred Ancestry (80% cut-off)
	Average of PDX Samples	13%	0%	0%	87%	West African (YRI)

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Patient Specimen Information

View	Specimen ID	Biopsy Site	Tissue Type	Growth Curve Avail	Archived	Age at Sampling	Collection Date
	202-R	Bone/Soft Tissue [L Knee]	Resection	No	No	38	07/2016

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