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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Patient

Value Required

562452

Disease Body Location

Breast

IDC

10006190 - Invasive breast carcinoma

Diagnosis Subtype

Ductal, TNBC

Date of Diagnosis

09/2018

Age at Diagnosis

45

NCI PDMR Models

Contributor PDX ID

Grade/Stage
Information Available

TNM (Clinical)

Has Known
Metastatic Disease

Tumor Grade/Stage: cT2N2

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Germline Whole Exome Sequence Files (if available)

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Limited Medical Information (provided after delinking)

Current Therapy

View	Date Regimen Started	Standardized Regimen	Best Response	Number of Cycles	Date of Progression or Off Therapy	Comments	Reason for Off Therapy
		No Current Therapy	NA	0

Prior Therapies and Response

View	Date Regimen Started	Standardized Regimen	Best Response	Duration Months	Comments
	10/2018	Paclitaxel	Stable Disease	3
	01/2019	Doxorubicin	Stable Disease	1

Additional Patient History

Molecular
and
IHC Data

IHC: ER+, PR-, HER2- (Patient undefined clinical time point. Note PDX model is TNBC)

Additional
Medical
History

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Social History (provided after delinking)

Social History

View	Ethnicity	Race	Occupation	Has Smoked 100 Cigarettes	Total Pack Years	Tobacco Use History
	Hispanic or Latino	Not Provided	unemployed	No	-	-

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Genetic Ancestry (SNPweights)

View	Source Sequence	%European (CEU)	%East Asian (EA)	%Native and Latin American (NA)	%West African (YRI)	Inferred Ancestry (80% cut-off)
	Germline Sequence	51%	0%	0%	49%	Mixed (All < 80%)

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Patient Specimen Information

View	Specimen ID	Biopsy Site	Tissue Type	Growth Curve Avail	Archived	Age at Sampling	Collection Date
	108-R	Breast [L]	Resection	Yes	No	46	04/2019

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