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Patient ID
128236
Biological Sex
<Unknown>
Male
Female
Disease Body Location
Digestive/Gastrointestinal
OncoTree Code
PAAD
CTEP SDC Code
10052747 - Adenocarcinoma - pancreas
Diagnosis Subtype
Date of Diagnosis
07/2019
Age at Diagnosis
74
Contributor
NCI PDMR Models
Contributor PDX ID
Grade/Stage
Information Available
Grade
Stage
TNM (Pathological)
Has Known
Metastatic Disease
Yes
Not Reported
Patient Notes
Tumor Grade/Stage: Stage IIB; pT2 pN1 M0; moderately differentiated
Primary tumor location: head of pancreas
Location of known metastases: liver, peritoneal carcinomatosis, lymph nodes, omentum, diffuse serosal surfaces
STR Profile
Download
Germline Whole Exome Sequence Files (if available)
External Germline Whole Exome Sequence Data
A data file is available if a Download link is displayed:
Germline Whole Exome Sequencing (*.vcf)
Germline Whole Exome FASTQ (*.FASTQ.gz; for paired-end sequence, download both files)
Limited Medical Information (provided after delinking)
Current Therapy
View
Date Regimen
Started
Standardized
Regimen
Best
Response
Number of
Cycles
Date of
Progression or
Off Therapy
Comments
Reason for
Off Therapy
No Current Therapy
NA
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Prior Therapies and Response
View
Date Regimen
Started
Standardized
Regimen
Best
Response
Duration
Months
Comments
01/2001
Radiation
NA
Additional details unknown; treatment for prior breast cancer
07/2018
FOLFIRINOX
Disease Progression
5
mFOLFIRINOX; 10 cycles
01/2019
FOLFIRI
Disease Progression
1
2 cycles
02/2019
Gemcitabine, nab-Paclitaxel
Disease Progression
6
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Additional Patient History
Molecular
and
IHC Data
Additional
Medical
History
Final Pathology: Dx confirmed; 2/22 lymph nodes positive for disease at diagnosis, positive lymphovascular invasion. PanIN 1B noted.
Prior malignancy: Breast cancer (>15yrs prior)
Additional Medical Hx: scleroderma
Social History (provided after delinking)
Social History
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Ethnicity
Race
Occupation
Has Smoked
100 Cigarettes
Total
Pack Years
Tobacco Use
History
Not Provided
White
Unknown
Yes
30
-
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1 - 1
Genetic Ancestry (SNPweights)
View
Source
Sequence
%European (CEU)
%East Asian (EA)
%Native and Latin American (NA)
%West African (YRI)
Inferred Ancestry
(80% cut-off)
Average of PDX Samples
100%
0%
0%
0%
European (CEU)
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Patient Specimen Information
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Specimen ID
Biopsy Site
Tissue Type
Growth Curve Avail
Archived
Age at Sampling
Collection Date
265-R3
Soft Tissue Mass [perisplenic]
Resection
No
No
75
09/2019
265-R4
Omentum
Resection
Yes
No
75
09/2019
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