Skip to Content
Contact PDMR
|
PDMR Database User Guide
Home
Patient
Patient Specimen
Sample (PDX or In Vitro Culture)
Distribution Lots
Genomic Analysis
Reports
Search
Patient
Cancel
Patient ID
253963
Biological Sex
<Unknown>
Male
Female
Disease Body Location
Breast
OncoTree Code
BRCNOS
CTEP SDC Code
10006190 - Invasive breast carcinoma
Diagnosis Subtype
TNBC
Date of Diagnosis
09/2022
Age at Diagnosis
58
Contributor
NCI PDMR Models
Contributor PDX ID
Grade/Stage
Information Available
Nottingham/Elston-Ellis
TNM (Pathological)
Has Known
Metastatic Disease
Yes
Not Reported
Patient Notes
Tumor Grade/Stage: Grade 3 (3+3+3), high-grade; pT2 pN0(sn) (pTNM, AJCC 8th ed.)
STR Profile
Download
Germline Whole Exome Sequence Files (if available)
External Germline Whole Exome Sequence Data
A data file is available if a Download link is displayed:
Germline Whole Exome Sequencing (*.vcf)
Germline Whole Exome FASTQ (*.FASTQ.gz; for paired-end sequence, download both files)
Limited Medical Information (provided after delinking)
Current Therapy
View
Date Regimen
Started
Standardized
Regimen
Best
Response
Number of
Cycles
Date of
Progression or
Off Therapy
Comments
Reason for
Off Therapy
Treatment naive
NA
0
Export
Prior Therapies and Response
View
Date Regimen
Started
Standardized
Regimen
Best
Response
Duration
Months
Comments
Treatment naive
NA
0
Export
Additional Patient History
Molecular
and
IHC Data
IHC: ER/PR/HER2-; chromogranin-, CK20-, CK5/6-, pancytokeratin AE1/AE3-; CD56+ (diffuse), CK7+ (partial), synaptophysin w/limited blush staining; Ki-67 >90%
Additional
Medical
History
Final Pathology: Dx confirmed; skeletal muscle invasion identified.
Enrolled as Large Cell Neuroendocrine carcinoma (LCNEC - breast) TNBC, PDX histology does not support LCNEC; diagnosis details revised.
Social History (provided after delinking)
Social History
View
Ethnicity
Race
Occupation
Has Smoked
100 Cigarettes
Total
Pack Years
Tobacco Use
History
Not Hispanic or Latino
Black or African American
transportation coordinator
No
-
-
Export
1 - 1
Genetic Ancestry (SNPweights)
View
Source
Sequence
%European (CEU)
%East Asian (EA)
%Native and Latin American (NA)
%West African (YRI)
Inferred Ancestry
(80% cut-off)
Originator Sequence
1%
0%
0%
99%
West African (YRI)
Export
1 - 1
Patient Specimen Information
View
Specimen ID
Biopsy Site
Tissue Type
Growth Curve Avail
Archived
Age at Sampling
Collection Date
270-R
Breast [RUIQ]
Resection
Yes
No
58
09/2022
Export
1 - 1