Patient Editor

Patient

Patient ID

144983

Biological Sex

Disease Body Location

Gynecologic

OncoTree Code

HGONEC

CTEP SDC Code

10033272 - Ovarian cancer, NOS

Diagnosis Subtype

large cell neuroendocrine carcinoma (LCNC) of the ovary

03/2018

NCI PDMR Models

Grade/Stage
Information Available

FIGO Stage
TNM (Pathological)

Has Known
Metastatic Disease

Patient Notes

Tumor Grade/Stage: FIGO grade 2; pT3a pN1a pM1; FIGO Stage IVB, Poorly differentiated

STR Profile

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Germline Whole Exome Sequence Files (if available)

Limited Medical Information (provided after delinking)

Current Therapy

View	Date Regimen Started	Standardized Regimen	Best Response	Number of Cycles	Date of Progression or Off Therapy	Comments	Reason for Off Therapy
		Treatment naive	NA	0

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Prior Therapies and Response

View	Date Regimen Started	Standardized Regimen	Best Response	Duration Months	Comments
		Treatment naive	NA	0

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Additional Patient History

Molecular
and
IHC Data

IHC: Ki-67 increased >90% proliferation index; WT1-, Synaptophysin+, Pankeratin+; BRG1/SMARCA4 lost in tumor cells.

Additional
Medical
History

Final patient pathology: Dx confirmed, lymphovascular invasion present; uterus with some evidence of unequivocal endometrioid adenocarcinoma, FIGO Grade 1. Extensive tumor involvement of all reproductive organs, pelvic wall and omentum.

Social History (provided after delinking)

Social History

View	Ethnicity	Race	Occupation	Has Smoked 100 Cigarettes	Total Pack Years	Tobacco Use History
	Not Provided	Black or African American	unknown	No	-	-

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Genetic Ancestry (SNPweights)

View	Source Sequence	%European (CEU)	%East Asian (EA)	%Native and Latin American (NA)	%West African (YRI)	Inferred Ancestry (80% cut-off)
	Germline Sequence	1%	0%	0%	99%	West African (YRI)

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Patient Specimen Information

View	Specimen ID	Biopsy Site	Tissue Type	Growth Curve Avail	Archived	Age at Sampling	Collection Date
	106-R	Ovary [R]	Resection	Yes	No	43	04/2018

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