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Patient ID
425362
Open Patient
Specimen ID
245-T
Disease Body Location
Skin
OncoTree Code
MEL
CTEP SDC Code
10053571 - Melanoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Tumor Biopsy
Tissue Collected
Scalp
Provided Tissue Origin
Primary
Collection Date
09/2015
Age at Sampling
47
General Model Information
Model Notes
PDOrg IHC/Path: Melanin A+
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*01:01
A*29:02
B*08:01
B*40:01
C*03:04
C*07:01
4/4
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Lung, Kidney, Liver, Pancreas
Timing of Observed Metastasis
Spontaneous Metastasis
Penetrance
40% (n=10, spontaneous); 100% (n-10, post-debulking)
TCIA Imaging Data Available
Yes
Link to TCIA
https://doi.org/10.7937/TCIA.2020.7YRS-7J97
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
3
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
Organoid Culture
425362-245-T-V1-organoid
17
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDC: Mixed Tumor Culture
425362-245-T-J1-PDC
26
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
425362-245-T
2
Available
Not Applicable
Available
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDC: Mixed Tumor Culture
J1-PDC
No
Yes
Yes
Yes
Yes
PDX
AY7
No
0
Yes
Yes
Yes
Yes
PDX
AY7U79
No
1
Yes
Yes
Yes
Yes
PDX
AY7U82
No
1
Yes
Yes
Yes
Yes
PDX
AY7U79TS4
No
2
Yes
No
No
No
PDX
AY7U81T63
No
2
Yes
Yes
Yes
Yes
PDX
AY7U82TT2
No
2
Yes
No
No
No
Export
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