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Patient ID
397859
Open Patient
Specimen ID
316-R
Disease Body Location
Breast
OncoTree Code
IDC
CTEP SDC Code
10006190 - Invasive breast carcinoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Breast [R]
Provided Tissue Origin
Primary
Collection Date
11/2015
Age at Sampling
85
General Model Information
Model Notes
PDX IHC/Path: ER-, PR-, Her2- (2+)
PDX Derivation/Growth: P0 tumors pooled from two viable tumors (P0POOL), implanted to mammary fat pad (OT) and then passaged subcutaneously; ulceration noted in higher passages.
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*02:01
A*25:01
B*44:02
B*44:03
C*05:01
C*16:01
6/6
PAM50 Classifier
Basal
PDX Metastatic in NSG?
Not Observed
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
3
4
5
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
CAF Culture
397859-316-R-J1-CAF
11
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
397859-316-R
5
Available
Not Applicable
Available Upon Request
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
CAF Culture
J1-CAF
No
Yes
No
No
No
PDX
Y76
No
0
Yes
No
No
No
PDX
Y80
No
0
Yes
No
No
No
PDX
P0POOL_OT-Q23
No
1
Yes
Yes
Yes
Yes
PDX
P0POOL_OT-Q25
No
1
Yes
Yes
Yes
Yes
PDX
P0POOL_OT-Q23N59
No
2
Yes
Yes
Yes
Yes
PDX
P0POOL_OT-Q25_RG-NP9
No
2
Yes
Yes
Yes
Yes
PDX
P0POOL_OT-Q23N60KY7W19
No
4
Yes
Yes
Yes
Yes
PDX
P0POOL_OT-Q23N60N00UE1X09
No
5
No
Yes
Yes
Yes
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
Yes
Yes
Yes
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