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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

731979

Value Required

095-R

Disease Body Location

Breast

IDC

10006190 - Invasive breast carcinoma

Human Pathogen
Testing Summary

Negative

Resection

Tissue Collected

Liver

Provided Tissue Origin

Metastatic Site

Collection Date

04/2017

Age at Sampling

39

General Model Information

PDX IHC/Path: ER-, PR-, Her2-,

NGS Characterization

Amplified: ERBB2 not amplified

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Mammary Fat Pad

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*03:01	A*29:02	B*44:02	B*44:03	C*07:04	C*16:01	6/6

PAM50 Classifier

Basal

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	PDX	731979-095-R	3	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	PDX	AL-VAY	No	0	Yes	No	No	No
	PDX	AL-VJW	No	0	Yes	Yes	Yes	Yes
	PDX	AL-VAY_AL-W08	No	1	Yes	Yes	Yes	Yes
	PDX	AL-VAY_AL-W10	No	1	Yes	Yes	Yes	Yes
	PDX	AL-VAY_AL-W13_AL-P28	No	2	Yes	Yes	Yes	Yes
	PDX	AL-VAY_AL-W13_AL-P30	No	2	Yes	Yes	Yes	Yes
	PDX	AL-VAY_AL-W13_AL-P28_AL-U19	No	3	Yes	Yes	Yes	Yes

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