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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

748385

Value Required

122-R

Disease Body Location

Breast

IDC

10006190 - Invasive breast carcinoma

Human Pathogen
Testing Summary

Negative

Resection

Tissue Collected

Breast [R]

Provided Tissue Origin

Primary

Collection Date

05/2017

Age at Sampling

66

General Model Information

PDX IHC/Path: ER+,PR-,Her2- (1+)

NGS Characterization

Amplified: ERBB2 not amplified

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Mammary Fat Pad

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*01:01	A*01:01	B*08:01	B*08:01	C*07:01	C*07:01	6/6

PAM50 Classifier

Basal

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

Growth Curve Analysis

View	Passage	Growth Curve	Growth Curve Notes
	0
	1
	2
	3
	4		There is a drop in the graph for all animals at ~583 days that looks like a data recording error.

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	PDX	748385-122-R	3	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	PDX	X1G	No	0	Yes	Yes	Yes	Yes
	PDX	X1GM092J94	No	2	Yes	Yes	Yes	Yes
	PDX	X1GH06	No	1	Yes	Yes	Yes	Yes
	PDX	X1GH07	No	1	Yes	Yes	Yes	Yes
	PDX	X1GH07G96_AL-KU5	No	3	Yes	Yes	Yes	Yes
	PDX	X1GH07G96_AL-KV2	No	3	Yes	Yes	Yes	Yes
	Patient/Originator Specimen	ORIGINATOR	Yes		No	Yes	Yes	Yes

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