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Patient ID
447297
Open Patient
Specimen ID
187-R
Disease Body Location
Breast
OncoTree Code
IDC
CTEP SDC Code
10006190 - Invasive breast carcinoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Breast [L]
Provided Tissue Origin
Primary
Collection Date
07/2017
Age at Sampling
63
General Model Information
Model Notes
PDX IHC/Path: ER-,PR-,Her2- (1+), GATA-3+ (diffuse), GCDFP-15+ (focal)
PDX Derivation/Growth: Alternative implant site [AL] is mammary fat pad. Recommend growth in MFP
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Mammary Fat Pad
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*01:01
A*26:01
B*15:18
B*38:01
C*07:04
C*12:03
5/5
PAM50 Classifier
Basal
PDX Metastatic in NSG?
Not Observed
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
3
4
5
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
CAF Culture
447297-187-R-J1-CAF
16
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
Organoid Culture
447297-187-R-V4-organoid
15
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
447297-187-R
5
Available
Not Applicable
Available Upon Request
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
CAF Culture
J1-CAF
No
Yes
No
No
No
Organoid Culture
V4-organoid
No
Yes
Yes
Yes
Yes
PDX
AL-WXY
No
0
Yes
No
No
No
PDX
AL-WYC
No
0
Yes
Yes
Yes
Yes
PDX
AL-WYA
No
0
Yes
No
No
No
PDX
AL-WYC_AL-GV6
No
1
Yes
Yes
Yes
Yes
PDX
AL-WYC_AL-GV7
No
1
Yes
Yes
Yes
Yes
PDX
AL-WYC_AL-GV7_AL-A31
No
2
Yes
No
No
No
PDX
AL-WYC_AL-GV7_AL-A32_AL-N45
No
3
Yes
Yes
Yes
Yes
PDX
AL-WYC_AL-GV7_AL-A32_AL-N37_AL-T78
No
4
Yes
Yes
Yes
Yes
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