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Patient Specimen
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Patient ID
415267
Open Patient
Specimen ID
285-R
Disease Body Location
Breast
OncoTree Code
IBC
CTEP SDC Code
10021980 - Inflammatory breast carcinoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Breast [L]
Provided Tissue Origin
Primary
Collection Date
10/2017
Age at Sampling
73
General Model Information
Model Notes
PDX IHC/Path: ER-,PR-,Her2- (1+). Poorly differentiated carcinoma of breast with metaplastic changes.
NGS Characterization
Amplified: ERBB2 not amplified
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*02:02
A*33:03
B*53:01
B*53:01
C*03:02
C*04:01
7/7
PAM50 Classifier
Basal
PDX Metastatic in NSG?
Not Observed
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
3
4
There is a drop in the graph at ~388 days that looks like a data recording error.
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
CAF Culture
415267-285-R-J1-CAF
12
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
Organoid Culture
415267-285-R-V1-organoid
16
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDC: Mixed Tumor Culture
415267-285-R-J2-PDC
26
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
415267-285-R
3
Available
Not Applicable
Available Upon Request
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
CAF Culture
J1-CAF
No
Yes
No
No
No
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDC: Mixed Tumor Culture
J2-PDC
No
Yes
Yes
Yes
Yes
PDX
AK3
No
0
Yes
Yes
Yes
Yes
PDX
AK4
No
0
Yes
No
No
No
PDX
AK5
No
0
Yes
No
No
No
PDX
AK3JG4
No
1
Yes
Yes
Yes
Yes
PDX
AK3JG5K68C67
No
3
Yes
Yes
Yes
Yes
PDX
AK6
No
0
Yes
Yes
Yes
Yes
PDX
AK3JJ0C83
No
2
Yes
Yes
Yes
Yes
PDX
AK3JG5K66
No
2
Yes
Yes
Yes
Yes
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
Yes
Yes
Yes
Export
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