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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

133474

Value Required

215-R6

Disease Body Location

Digestive/Gastrointestinal

IHCH

10004669 - Cholangiocar.- intra/extrahepatic

Human Pathogen
Testing Summary

Negative

Resection

Tissue Collected

Lung [RLL]

Provided Tissue Origin

Metastatic Site

Collection Date

08/2023

Age at Sampling

37

General Model Information

PDX and PDC CLX Path/IHC: Rhabdoid features observed

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*01:01	A*26:01	B*07:02	B*57:01	C*06:02	C*07:02	6/6

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	Organoid Culture	133474-215-R6-V2-organoid	11	Not Applicable	Available	Not Applicable	Not Applicable	Not Applicable
	PDX	133474-215-R6	2	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	Organoid Culture	V2-organoid	No		Yes	Yes	Yes	Yes
	PDX	PVN	No	0	Yes	Yes	Yes	Yes
	PDX	PVT	No	0	Yes	No	No	No
	PDX	ORIGINATOR	Yes		Yes	Yes	Yes	Yes
	PDX	PVP	No	0	Yes	Yes	Yes	Yes
	PDX	PVPR24	No	1	Yes	Yes	Yes	Yes
	PDX	PVPR25	No	1	Yes	Yes	Yes	Yes
	PDX	PVPR21T33	No	2	Yes	Yes	Yes	Yes
	PDX	PVPR24T26	No	2	Yes	Yes	Yes	Yes

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