Specimen Editor

Specimen

Patient ID

128162

Specimen ID

247-R

Disease Body Location

Breast

OncoTree Code

IDC

CTEP SDC Code

10006190 - Invasive breast carcinoma

Human Pathogen
Testing Summary

Negative

Tissue Type

Resection

Tissue Collected

Lymph node [L Axillary]

Provided Tissue Origin

Metastatic Site

Collection Date

09/2019

Age at Sampling

General Model Information

Model Notes

PDX IHC/Path: TNBC, IHC: ER-, PR-, Her2-
PDX Derivation Notes: Alternative implant site [AL] is Mammary Fat Pad (MFP). Estradiol not required for growth

NGS Characterization

Amplified: MYC, AGO2

Able to Viably Passage
into Athymic Nude Mice?

Unknown

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Mammary Fat Pad

MSI Status

MSI-Stable

HLA Profile(s)

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*02:11	A*24:02	B*07:05	B*15:05	C*03:03	C*03:03	2/6
A*02:11	A*24:02	B*07:05	B*15:05	C*03:03	C*03:04	4/6

PAM50 Classifier

Basal

PDX Metastatic in NSG?

Not Observed

PDX Growth Curve Data (if available)

Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	Organoid Culture	128162-247-R-V1-organoid	12	Not Applicable	Available	Not Applicable	Not Applicable	Not Applicable
	PDX	128162-247-R	2	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

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Sample (PDX)

PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
Organoid Culture	V1-organoid	No		Yes	Yes	Yes	Yes
PDX	AL-NQ6	No	0	Yes	Yes	Yes	Yes
PDX	AL-NQ7	No	0	Yes	No	No	No
PDX	AL-NQ9	No	0	Yes	Yes	Yes	Yes
PDX	AL-NQ6_AL-T93	No	1	Yes	Yes	Yes	Yes
PDX	AL-NQ9_AL-U84	No	1	Yes	Yes	Yes	Yes
PDX	AL-NQ7_AL-U52	No	1	Yes	Yes	Yes	Yes
PDX	AL-NQ6_AL-T93_AL-W64	No	2	Yes	Yes	Yes	Yes

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