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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

114348

Value Required

004-R

Disease Body Location

Digestive/Gastrointestinal

READ

10038045 - Adenocarcinoma - rectum

Human Pathogen
Testing Summary

Negative

Resection

Tissue Collected

Colon [LAR & Rectosigmoid]

Provided Tissue Origin

Primary

Collection Date

01/2016

Age at Sampling

46

General Model Information

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*02:01	A*25:01	B*08:01	B*14:02	C*07:01	C*08:02	5/5

CMS2

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

Growth Curve Analysis

View	Passage	Growth Curve	Growth Curve Notes
	0
	1
	2
	3		There is a drop in the graph for all groups at ~566 days that looks like a data recording error.

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	PDX	114348-004-R	3	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	PDX	ATH	No	0	Yes	Yes	Yes	No
	PDX	ATHY22	No	1	Yes	Yes	Yes	Yes
	PDX	ATHY22E99	No	2	Yes	Yes	Yes	Yes
	PDX	ATHY24	No	1	Yes	Yes	Yes	Yes
	PDX	ATHY24P18	No	2	Yes	Yes	Yes	Yes
	PDX	ATHY24P18AE8	No	3	Yes	No	No	No

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