Specimen Editor

Specimen

Patient ID

112475

Specimen ID

105-R

Disease Body Location

Gynecologic

OncoTree Code

SOC

CTEP SDC Code

10033159 - Ovarian epithelial cancer

Human Pathogen
Testing Summary

Negative

Tissue Type

Resection

Tissue Collected

Peritoneum

Provided Tissue Origin

Metastatic Site

Collection Date

04/2016

Age at Sampling

General Model Information

Model Notes

PDX IHC/Path: ER+, PR+
PDX Derivation/Growth: Estradiol not required for growth

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI Status

MSI-Stable

HLA Profile(s)

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*02:01	A*03:01	B*15:01	B*44:02	C*03:03	C*15:02	6/6

PDX Metastatic in NSG?

Not Observed

PDX Growth Curve Data (if available)

Growth Curve Analysis

View	Passage	Growth Curve	Growth Curve Notes
	0
	1
	2		Wide variability/heterogeneity in growth rates, curves for 2 PDXs shown to demonstrate range of growth rates
	3
	4
	5

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	PDX	112475-105-R	4	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

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Sample (PDX)

PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
PDX	G2W	No	0	Yes	No	No	No
PDX	G2U	No	0	Yes	Yes	Yes	Yes
PDX	G2V	No	0	Yes	No	No	No
PDX	G2UN86	No	1	Yes	Yes	Yes	Yes
PDX	G2UN84PK7	No	2	Yes	Yes	Yes	Yes
PDX	G2WP48PG4	No	2	Yes	Yes	Yes	Yes
PDX	G2UN84PK7VP2	No	3	Yes	Yes	Yes	Yes
PDX	G2UN84PK7VP5Y62	No	4	Yes	Yes	Yes	Yes
Patient/Originator Specimen	ORIGINATOR	Yes		Yes	No	No	No

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