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Patient ID
695669
Open Patient
Specimen ID
166-R
Disease Body Location
Skin
OncoTree Code
MEL
CTEP SDC Code
10053571 - Melanoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Arm [R. upper proximal]
Provided Tissue Origin
Primary
Collection Date
06/2015
Age at Sampling
66
General Model Information
Model Notes
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Unknown
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*30:02
A*30:02
B*49:01
B*49:01
C*07:01
C*07:01
6/6
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Liver, lung, lymph node, pancreas, salivary gland, peritoneum, fat pads
Timing of Observed Metastasis
Post De-bulking Metastasis
Penetrance
36% (n=25, 61d)
TCIA Imaging Data Available
No
Link to TCIA
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
2 of 4 models were passaged/sac'd ~125 days and 1 ~178 days creating appearance of growth rate declines.
1
2
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
PDX
695669-166-R
2
Available
Not Applicable
Available
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
PDX
WR7
No
0
Yes
Yes
Yes
Yes
PDX
WR8
No
0
Yes
No
No
No
PDX
WR6
No
0
Yes
Yes
Yes
Yes
PDX
WR5
No
0
Yes
No
No
No
PDX
WR6VC5
No
1
Yes
Yes
Yes
Yes
PDX
WR6VC6
No
1
Yes
Yes
Yes
Yes
PDX
WR7V96
No
1
Yes
Yes
Yes
Yes
PDX
WR8VB8
No
1
Yes
Yes
Yes
Yes
Export
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