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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

172845

Value Required

121-T

Disease Body Location

Digestive/Gastrointestinal

COAD

10009951 - Adenocarcinoma - colon

Human Pathogen
Testing Summary

Negative

Tumor Biopsy

Tissue Collected

Liver

Provided Tissue Origin

Metastatic Site

Collection Date

05/2013

Age at Sampling

46

General Model Information

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Unknown

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*01:01	A*32:01	B*08:01	B*14:01	C*07:01	C*08:02	6/6

CMS3

PDX Metastatic in NSG?

Yes

Location of Observed Metastases

Lung

Timing of Observed Metastasis

Spontaneous & Post De-bulking Metastasis

12% (n=16, spontaneous); 21% (n=19, de-bulking)

TCIA Imaging Data Available

No

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PDX Growth Curve Data (if available)

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	PDX	172845-121-T	2	Available	Not Applicable	Available	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	PDX	M776M1151	No	1	Yes	Yes	Yes	Yes
	PDX	M776M1153	No	1	Yes	No	No	No
	PDX	M776	No	0	Yes	Yes	Yes	Yes
	PDX	M776M1154	No	1	Yes	No	No	No
	PDX	M777	No	0	Yes	No	No	No
	PDX	M776M1154J15	No	2	Yes	Yes	Yes	Yes
	PDX	M776M1155J93	No	2	Yes	Yes	Yes	Yes
	PDX	M776M1152J66	No	2	Yes	Yes	Yes	Yes
	PDX	M776M1153J58	No	2	Yes	Yes	Yes	Yes

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