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Patient ID
997537
Open Patient
Specimen ID
175-T
Disease Body Location
Digestive/Gastrointestinal
OncoTree Code
COAD
CTEP SDC Code
10009951 - Adenocarcinoma - colon
Human Pathogen
Testing Summary
Negative
Tissue Type
Tumor Biopsy
Tissue Collected
Liver
Provided Tissue Origin
Metastatic Site
Collection Date
06/2016
Age at Sampling
74
General Model Information
Model Notes
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-High
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*01:01
A*02:01
B*08:01
B*35:03
C*07:01
C*12:03
4/4
CMS Category
CMS1
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Lung, Lymph node
Timing of Observed Metastasis
Spontaneous & Post De-bulking Metastasis
Penetrance
60% (n=10, spontaneous); 100% (n=10, de-bulking)
TCIA Imaging Data Available
Yes
Link to TCIA
https://doi.org/10.7937/TCIA.2020.BRY9-4N29
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
Organoid Culture
997537-175-T-V1-organoid
8
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDC: Mixed Tumor Culture
997537-175-T-J1-PDC
18
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
997537-175-T
2
Available
Not Applicable
Available
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDC: Mixed Tumor Culture
J1-PDC
No
Yes
Yes
Yes
Yes
PDX
HP1
No
0
Yes
Yes
Yes
Yes
PDX
HN1
No
0
Yes
Yes
Yes
Yes
PDX
HN1G62
No
1
Yes
Yes
Yes
Yes
PDX
HP1G72
No
1
Yes
Yes
Yes
Yes
PDX
HP1G74H61
No
2
Yes
No
No
No
PDX
HP1G74H65
No
2
Yes
No
No
No
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
No
No
No
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