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Patient ID
765638
Open Patient
Specimen ID
272-R
Disease Body Location
Respiratory/Thoracic
OncoTree Code
LUSC
CTEP SDC Code
10025126 - Squamous cell lung carcinoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Liver [R]
Provided Tissue Origin
Metastatic Site
Collection Date
09/2014
Age at Sampling
72
General Model Information
Model Notes
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Unknown
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*02:01
A*02:01
B*40:01
B*44:02
C*01:02
C*03:04
5/5
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Lung, liver
Timing of Observed Metastasis
Spontaneous & Post De-bulking Metastasis
Penetrance
3% (n=30, 42d, spontaneous); 10% (n=30, 60d, de-bulking)
TCIA Imaging Data Available
No
Link to TCIA
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
3 of 4 models were passaged/sac'd ~70 days and ~83 days creating appearance of growth rate decline.
1
2
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
PDX
765638-272-R
2
Available
Not Applicable
Available
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
PDX
AG3
No
0
Yes
No
No
No
PDX
AG1
No
0
Yes
Yes
Yes
Yes
PDX
AG4
No
0
Yes
No
No
No
PDX
AG2
No
0
Yes
Yes
Yes
Yes
PDX
AG3AX5
No
1
Yes
Yes
Yes
Yes
PDX
AG2I09
No
1
Yes
Yes
Yes
Yes
PDX
AG4I00
No
1
Yes
No
No
No
PDX
AG4I01IB7
No
2
Yes
Yes
Yes
Yes
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
No
No
Yes
Export
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