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Patient ID
292921
Open Patient
Specimen ID
168-R
Disease Body Location
Digestive/Gastrointestinal
OncoTree Code
PAAD
CTEP SDC Code
10052747 - Adenocarcinoma - pancreas
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Pancreas
Provided Tissue Origin
Primary
Collection Date
06/2015
Age at Sampling
64
General Model Information
Model Notes
PDX IHC/Path: CK+, CD45-, EBV-, HuMit+. Poorly differentiated carcinoma NOS; cannot confirm patient diagnosis in PDX.
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Unknown
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-High
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*01:01
A*26:01
B*15:01
B*38:01
C*03:04
C*12:03
6/6
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Lung, Kidney, Lymph nodes, Peritoneal Wall
Timing of Observed Metastasis
Spontaneous & Post De-bulking Metastasis
Penetrance
40% (n=10, spontaneous); 100% (n=10, de-bulking)
TCIA Imaging Data Available
Yes
Link to TCIA
https://doi.org/10.7937/TCIA.2020.PCAK-8Z10
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1 of 4 models were passaged/sac'd ~97 days creating appearance of growth rate decline.
1
2
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
Organoid Culture
292921-168-R-V1-organoid
10
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
292921-168-R
2
Available
Not Applicable
Available Upon Request
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDX
WS0
No
0
Yes
Yes
Yes
Yes
PDX
WS1
No
0
Yes
No
No
No
PDX
WS2
No
0
Yes
Yes
Yes
Yes
PDX
WS3
No
0
Yes
No
No
No
PDX
WS0Y22
No
1
Yes
Yes
Yes
Yes
PDX
WS0Y23Y42
No
2
Yes
Yes
Yes
Yes
PDX
WS1V43
No
1
Yes
Yes
Yes
Yes
PDX
WS1V44VC0
No
2
Yes
Yes
Yes
Yes
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