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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

865297

Value Required

335-R

Disease Body Location

Skin

MEL

10053571 - Melanoma

Human Pathogen
Testing Summary

Negative

Resection

Tissue Collected

Lymph Node [R Axillary]

Provided Tissue Origin

Metastatic Site

Collection Date

12/2021

Age at Sampling

58

General Model Information

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*24:02	A*26:01	B*38:01	B*55:01	C*03:03	C*12:03	6/6

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	Organoid Culture	865297-335-R-V1-organoid	22	Not Applicable	Available	Not Applicable	Not Applicable	Not Applicable
	PDX	865297-335-R	2	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	Organoid Culture	V1-organoid	No		Yes	Yes	Yes	Yes
	PDX	AW3	No	0	Yes	Yes	Yes	Yes
	PDX	AW4	No	0	Yes	Yes	Yes	Yes
	PDX	AW6	No	0	Yes	No	No	No
	PDX	AW7T42	No	1	Yes	Yes	Yes	Yes
	PDX	AW7T41	No	1	Yes	No	No	No
	PDX	AW7T43	No	1	Yes	No	No	No
	PDX	AW7T45	No	1	Yes	No	No	No
	PDX	AW3T01	No	1	Yes	Yes	Yes	Yes
	PDX	AW4T36	No	1	Yes	Yes	Yes	Yes
	PDX	AW4T36U73	No	2	Yes	Yes	Yes	Yes

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