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Patient ID
885512
Open Patient
Specimen ID
296-R
Disease Body Location
Breast
OncoTree Code
MMBC
CTEP SDC Code
10006190 - Invasive breast carcinoma
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Breast [L]
Provided Tissue Origin
Primary
Collection Date
10/2018
Age at Sampling
74
General Model Information
Model Notes
PDX IHC/Path: ER-,PR-,Her2-, CK+, p63+; Mixed metaplastic Squamous cell outgrowth
PDOrg IHC/Path: p63+, GATA3+, S100+ (focal), Suggestive of metaplastic breast carcinoma (SCC).
PDC Derivation/Growth: CLX alternative implant site MFP
NGS Characterization
Amplified: ERBB2 not amplified
Able to Viably Passage
into Athymic Nude Mice?
Yes
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Mammary Fat Pad
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*02:01
A*29:02
B*45:01
B*51:05
C*04:01
C*06:02
6/6
PAM50 Classifier
Basal
PDX Metastatic in NSG?
Not Observed
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
1
2
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
Organoid Culture
885512-296-R-V1-organoid
19
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDC: Mixed Tumor Culture
885512-296-R-J2-PDC
18
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
885512-296-R
2
Available
Not Applicable
Available Upon Request
Available Upon Request
Available
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDC: Mixed Tumor Culture
J2-PDC
No
Yes
Yes
Yes
Yes
PDX
AL-KAE
No
0
Yes
No
No
No
PDX
AL-KAF
No
0
Yes
Yes
Yes
Yes
PDX
AL-KAG
No
0
Yes
No
No
No
PDX
AL-KAW
No
0
Yes
No
No
No
PDX
AL-KAG_AL-Q34
No
1
Yes
No
No
No
PDX
AL-KAF_AL-Q24
No
1
Yes
Yes
Yes
Yes
PDX
AL-KAG_AL-Q33
No
1
Yes
Yes
Yes
Yes
PDX
AL-KAW_AL-Q88
No
1
Yes
Yes
Yes
Yes
PDX
AL-KAG_AL-Q34_AL-T39
No
2
Yes
Yes
Yes
Yes
PDX
AL-KAE_AL-Q12
No
1
Yes
Yes
Yes
Yes
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
Yes
Yes
Yes
Export
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