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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Specimen

Value Required

447624

Value Required

303-R

Disease Body Location

Digestive/Gastrointestinal

ANSC

10041840 - Squamous cell carcinoma - anus

Human Pathogen
Testing Summary

HPV18+

Resection

Tissue Collected

Anal Mass

Provided Tissue Origin

Primary

Collection Date

10/2018

Age at Sampling

74

General Model Information

NGS Characterization

Able to Viably Passage
into Athymic Nude Mice?

Yes

Mouse Strain Used
for Engraftment

NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)

Viable Passage
Implantation Site

Subcutaneous (flank)

MSI-Stable

A1	A2	B1	B2	C1	C2	PDX Concordance / PDM Type
A*24:02	A*24:02	B*35:02	B*35:02	C*04:01	C*04:01	6/6

PDX Metastatic in NSG?

Not Observed

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PDX Growth Curve Data (if available)

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Consensus Genomic Variants from WES Files

Distribution Lots

View	PDM Type	Name	Max. Passage	Cryovial for PDX Generation	In Vitro Culture Material	PDX DNA Vials	PDX RNA Vials	PDX Flash- Frozen Vials
	Organoid Culture	447624-303-R-V1-organoid	17	Not Applicable	Available	Not Applicable	Not Applicable	Not Applicable
	PDC: Mixed Tumor Culture	447624-303-R-J1-PDC	38	Not Applicable	Available	Not Applicable	Not Applicable	Not Applicable
	PDX	447624-303-R	2	Available	Not Applicable	Available Upon Request	Available Upon Request	Available

Sample (PDX)

View	PDM Type	Sample ID	Patient/Originating Specimen	PDX Passage	Sample Images Avail	OncoKB Gene Panel Data	Whole Exome Sequence Avail	RNASeq Avail
	Organoid Culture	V1-organoid	No		Yes	Yes	Yes	Yes
	PDC: Mixed Tumor Culture	J1-PDC	No		Yes	Yes	Yes	Yes
	PDX	CAC	No	0	Yes	No	No	No
	PDX	CAA	No	0	Yes	Yes	Yes	Yes
	PDX	AA7	No	0	Yes	No	No	No
	PDX	AA7T29	No	1	Yes	Yes	Yes	Yes
	PDX	CACT50	No	1	Yes	Yes	Yes	Yes
	PDX	AA7T33U88	No	2	Yes	Yes	Yes	Yes
	PDX	CACT50U92	No	2	Yes	Yes	Yes	Yes
	PDX	CACT50U96	No	2	Yes	Yes	Yes	Yes

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