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OncoKB Gene Panel: Listing of All Nonsynonymous Variants in Genes of Interest; Variant May or May Not Play a Role in Cancer Predisposition
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Patient ID
117519
Open Patient
Specimen ID
064-T
Open Specimen
Sample ID
ED0D48
Open Sample
OncoKB Version
v3.14
Chr
chr17
Chr Start
7577117
Chr End
7577117
Ref Allele
A
Alt Allele
G
HGVS cDNA Change
c.821T>C
HGVS Protein Change
p.V274A
Existing Variant
TP53_g.13801T>C,COSM131453,COSM1640826,COSM1640827,COSM165076,COSM241993,COSM3701290,COSM3970339,COSM3970340,COSM43945,COSM44393,COSM44448,COSM4749451
Variant Class
Missense_Mutation
Total Reads
56
PolyPhen
probably_damaging(0.915)
Oncogenicity
Likely Oncogenic
Predicted
Functional Effect
Likely Loss-of-function