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OncoKB Gene Panel: Listing of All Nonsynonymous Variants in Genes of Interest; Variant May or May Not Play a Role in Cancer Predisposition
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Patient ID
425362
Open Patient
Specimen ID
245-T
Open Specimen
Sample ID
V1-organoid
Open Sample
OncoKB Version
v3.14
Chr
chr17
Chr Start
7577108
Chr End
7577108
Ref Allele
C
Alt Allele
T
HGVS cDNA Change
c.830G>A
HGVS Protein Change
p.C277Y
Existing Variant
rs763098116,CM078491,TP53_g.13810G>A,COSM10749,COSM1649337,COSM4271761,COSM43737,COSM44992,COSM562338
Variant Class
Missense_Mutation
Total Reads
216
PolyPhen
probably_damaging(0.986)
Oncogenicity
Likely Oncogenic
Predicted
Functional Effect
Likely Loss-of-function