Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

787684

078-R

Value Required

E1CQ70W27W77

Disease Body Location

Gynecologic

EOV

10033159 - Ovarian epithelial cancer

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

3

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	80%	0%	20%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.21.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.21.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.S21*	0.6151	278	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	APC	p.R1114*	0.3736	554	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	APC	p.R1450*	0.5500	280	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	ARID1B	p.G966S	0.4591	514	Missense_Mutation	Likely Oncogenic	Unknown	v4.6
	ARID4B	p.E868*	0.3099	242	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	ATM	p.M557Nfs*9	0.3080	237	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.6
	ATR	p.R1368*	0.3461	783	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	BRAF	p.K499N	0.5143	70	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v4.6
	BRCA2	p.E2121*	0.5556	108	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	CD58	p.E53*	0.6179	123	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	CHEK2	p.E321*	0.2677	198	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	CHEK2	p.Y297*	0.6481	54	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	CHEK2	p.E70*	0.2331	133	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	CTCF	p.E133*	0.3953	296	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	DTX1	p.R397*	0.3455	220	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	EED	p.R441*	0.6092	87	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	EZH2	p.R207Q	0.5239	565	Missense_Mutation	Inconclusive	Inconclusive	v4.6
	FAT1	p.X3881_splice	0.5129	349	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v4.6
	FAT1	p.R2556*	0.5000	234	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	FAT1	p.E1292*	0.5124	605	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	FGFR2	p.R203H	0.4904	208	Missense_Mutation	Likely Neutral	Likely Neutral	v4.6
	FH	p.E404*	0.3692	130	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	FUBP1	p.R344*	0.3415	284	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	INHA	p.E77*	0.1947	190	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	KMT2D	p.R3982*	0.3333	153	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	MAP3K1	p.E1441*	0.4157	178	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	MITF	p.E327*	0.3451	142	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	MSH2	p.E278*	0.4490	196	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	NCOR1	p.E1346*	0.4820	471	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	NF1	p.E163*	0.4348	46	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	NF1	p.R440*	0.4467	450	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	NOTCH1	p.V1671I	0.4778	90	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v4.6
	PBRM1	p.R1160*	0.7075	106	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	PBRM1	p.R710*	0.6833	240	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	PIK3R1	p.R162*	0.5613	579	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	PIK3R1	p.R348*	0.3895	665	Nonsense_Mutation	Oncogenic	Loss-of-function	v4.6
	PMS2	p.R563*	0.5370	365	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	POLE	p.P286R	0.6202	129	Missense_Mutation	Likely Oncogenic	Loss-of-function	v4.6
	PTEN	p.E7*	0.4948	97	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	PTEN	p.R173C	0.4375	64	Missense_Mutation	Likely Oncogenic	Loss-of-function	v4.6
	PTPRD	p.S431L	0.5268	298	Missense_Mutation	Likely Oncogenic	Unknown	v4.6
	PTPRT	p.R936*	0.5906	298	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	PTPRT	p.E166*	0.3529	119	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	RAD51B	p.E198*	0.4894	94	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	RASA1	p.E722*	0.5953	257	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	RASA1	p.R1010*	0.5619	493	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	RB1	p.E137*	1.0000	68	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	RB1	p.S648*	0.5345	348	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	SESN3	p.S308*	0.6933	163	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	SH2D1A	p.E119*	1.0000	16	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	SHQ1	p.E109*	0.4516	31	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	SPOP	p.R240*	0.5139	216	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	TBX3	p.X289_splice	0.7061	245	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v4.6
	TP53BP1	p.E288*	0.5061	330	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	TSC1	p.E485*	0.6809	47	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	XPO1	p.R749Q	0.5000	588	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v4.6
	XPO1	p.E571K	0.5132	265	Missense_Mutation	Oncogenic	Gain-of-function	v4.6
	ZFHX3	p.E2975*	0.4949	295	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	ZFHX3	p.R2668*	0.4721	502	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	ARHGAP35	p.E371*	1.0000	466	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	DOT1L	p.A1003T	0.5588	612	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v4.6
	RAD17	p.R301*	0.3023	86	Nonsense_Mutation	Likely Oncogenic	Loss-of-function	v4.6
	LRP1B	p.E2849*	0.2329	554	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.6
	LRP1B	p.X115_splice	0.2231	130	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v4.6

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