Sample Editor (PDX or In Vitro Culture)

Derived from pooled passage 0 PDX material. Mouse cells were depleted from organoid culture on two separate occasions using magnetic beads labeled with anti-mCD9 and anti-mMHC antibodies.

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

N/A

Soft Agar Growth

Soft Agar
Growth Notes

N/A

Fibroblast qRT-PCR
C1 Corr

0.55

Fibroblast qRT-PCR
C2 Corr

0.44

Fibroblast qRT-PCR
Top Hits

KRT16,FN1,VIM,KRT18,KRT8

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	Image of total well, 1 mm scale bar, Passage 23, 7 days in culture
	Light Microscopy	Magnified image, 500 micron scale bar, Passage 23, 7 days in culture
	Organoid H&E	10X image of embedded Patient-derived organoids
	Xenograft from In Vitro Culture	20X image of cell culture-derived xenograft

Export

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

2.0.2.51.0

2.0.2.21.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.2.21.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
NRAS	p.Q61R	0.9610	77	Missense_Mutation	Oncogenic	Gain-of-function	v4.11
PPP6C	p.R264C	0.9263	285	Missense_Mutation	Likely Oncogenic	Loss-of-function	v4.11
CHD4	p.E139del	0.0857	245	In_Frame_Del	Inconclusive	Inconclusive	v4.11

Export

1 - 3