Sample Editor (PDX or In Vitro Culture)

Skip to Content

NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

625472

104-R

Value Required

H70HC4

Disease Body Location

Digestive/Gastrointestinal

COAD

10009951 - Adenocarcinoma - colon

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

Hide or show region

Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	75%	%	25%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	ASXL1	p.G645Wfs*12	0.0000	124	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	ATRX	p.N633Tfs*16	0.3843	242	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	BCOR	p.R1514*	0.4783	69	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	BCORL1	p.M644Hfs*21	0.5131	536	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	BCORL1	p.Q798*	0.5553	470	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	BRAF	p.V600E	1.0000	52	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
	BRCA2	p.Y1220Ifs*8	0.7034	236	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	CASP8	p.R292W	0.5291	172	Missense_Mutation	Likely Oncogenic	Unknown	v3.14
	CCND3	p.P284L	1.0000	94	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v3.14
	CDKN1A	p.R83Gfs*65	0.5023	219	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	CDKN2A	p.D84N	0.5152	66	Missense_Mutation	Likely Oncogenic	Loss-of-function	v3.14
	DIS3	p.I678Ffs*59	0.3247	154	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	EPHA3	p.E647Rfs*9	0.4538	130	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	ESCO2	p.T254Nfs*27	0.4321	162	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	FOXL2	p.K193Sfs*78	0.4873	158	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	INPPL1	p.R1156Gfs*46	0.5385	78	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	JARID2	p.A396Rfs*18	0.4390	205	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	KMT2A	p.K3828Rfs*31	0.4854	206	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	KMT2D	p.R5340*	0.5543	92	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	MGA	p.D2578Tfs*10	0.4941	255	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	MSH2	p.A230Lfs*16	0.5399	213	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	MSH3	p.K383Rfs*32	0.5904	83	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	PIK3CA	p.C420R	0.4627	134	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
	RB1	p.R320*	0.7059	85	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	RB1	p.R418Kfs*10	0.3299	97	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	RIT1	p.A57D	0.1993	567	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v3.14
	RNF43	p.P660Vfs*41	0.9926	135	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	TET1	p.N486Ifs*6	0.5054	184	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14

1 - 28