Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

397859

316-R

Value Required

ORIGINATOR

Disease Body Location

Breast

IDC

10006190 - Invasive breast carcinoma

Value Required

Patient/Originator Specimen

Resection

Patient/Originating
Specimen

Passage of this Sample

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	40%	0%	60%	2+ (Moderate)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.16.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.16.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.N2624Gfs*21	0.1000	100	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	APC	p.T2626Ffs*13	0.0982	112	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1A	p.T2060Ifs*38	0.0679	427	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1A	p.Y2076Ifs*23	0.0754	464	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1B	p.S40Vfs*192	0.1084	203	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1B	p.S41Rfs*28	0.1073	205	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1B	p.L208Hfs*22	0.2200	50	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID1B	p.T210Sfs*56	0.2000	50	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID2	p.Q1835*	0.1553	103	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID4A	p.X1071_splice	0.9626	107	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v4.0
	ARID4B	p.E550Gfs*6	0.0816	380	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ATP6V1B2	p.Y371F	0.1603	131	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCL11B	p.L370Nfs*24	0.1525	118	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCL11B	p.E369Afs*147	0.1488	121	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.Q1248Pfs*47	0.0735	408	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.I1246Tfs*5	0.0764	419	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.D1226Efs*18	0.1013	316	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.D1226Efs*13	0.1049	305	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.D169Gfs*17	0.1149	261	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	BCOR	p.A165Gfs*51	0.1221	262	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	BTG1	p.E93Rfs*9	0.1111	270	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	BTG1	p.Q92Rfs*52	0.1159	276	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	CDK12	p.F1376Sfs*5	0.0917	338	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	CDK12	p.G1456Tfs*44	0.1000	240	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	CDK12	p.G1456Afs*56	0.1000	240	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	CEBPA	p.G101Rfs*6	0.1342	149	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	CEBPA	p.T98Afs*61	0.1402	164	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	DUSP4	p.A358Dfs*91	0.1746	126	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	DUSP4	p.P357Tfs*67	0.1789	123	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	FBXO11	p.L912Rfs*9	0.1184	304	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	FBXO11	p.T911Nfs*9	0.1331	323	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	FOXO1	p.P139Rfs*63	0.1376	109	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	FOXO1	p.A140Sfs*195	0.1250	104	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	HLA-A	p.D140Rfs*36	1.0000	3	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	HLA-A	p.A141Lfs*11	1.0000	3	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	KDM5C	p.T1228Lfs*71	0.1344	372	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	KDM5C	p.P1227Lfs*38	0.1316	380	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	KMT2D	p.S2312Wfs*13	0.1730	289	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	KMT2D	p.S2312Afs*11	0.1753	291	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	LATS2	p.P38Qfs*26	0.0769	286	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	LATS2	p.V34Rfs*30	0.0746	295	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	LATS2	p.V34Tfs*12	0.0759	290	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	LZTR1	p.R21Lfs*12	0.0598	468	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	MGA	p.A51*	0.1167	120	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	MGA	p.S52*	0.1034	116	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	MGA	p.A2917Gfs*7	0.0762	105	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	MGA	p.E2918Qfs*16	0.0833	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	MGA	-	0.1818	44	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	NSD1	p.S1937Qfs*8	0.1101	109	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	NSD1	p.K1938Afs*32	0.1009	109	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	PHF6	p.S158*	0.0809	136	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PIK3CA	p.Q546K	0.3333	189	Missense_Mutation	Oncogenic	Gain-of-function	v4.0
	PTCH1	p.R1342Afs*30	0.0893	224	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTCH1	p.A43Pfs*37	0.1414	99	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTCH1	p.A42Cfs*47	0.1400	100	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTCH1	p.G29Afs*50	0.1250	80	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTPN2	p.Q411Hfs*17	0.0435	253	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTPRD	p.D657Qfs*25	0.1233	365	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	PTPRD	p.D657Lfs*32	0.1236	364	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	RAD51	p.R235Qfs*27	0.1500	20	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	RB1	p.F839Sfs*10	1.0000	51	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	TP53	p.I195N	0.9917	484	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v4.0
	TP53BP1	p.I738Sfs*3	0.0905	221	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	TP53BP1	p.L736Cfs*4	0.0922	217	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	TP53BP1	p.L736Vfs*5	0.0930	215	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.P3605Rfs*90	0.1529	170	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.A3604Pfs*61	0.1600	175	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.H508Rfs*9	0.1048	105	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.H508Sfs*29	0.1100	100	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.S383Rfs*71	0.1238	323	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v4.0
	ZFHX3	p.G382Vfs*15	0.1265	324	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v4.0

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