Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

779769

127-R

Value Required

VS0DY7WQ3Z21

Disease Body Location

Digestive/Gastrointestinal

READ

10038045 - Adenocarcinoma - rectum

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

3

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	55%	%	45%	2+ (Moderate)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.R805*	1.0000	134	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	ATM	p.F858L	0.2985	268	Missense_Mutation	Likely Neutral	Likely Neutral	v3.14
	ERCC2	p.X459_splice	0.6397	272	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v3.14
	KRAS	p.A146T	0.6557	122	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
	PIK3R1	p.S171Pfs*6	0.4809	418	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	TP53	p.R273H	1.0000	91	Missense_Mutation	Oncogenic	Loss-of-function	v3.14

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