Sample Editor (PDX or In Vitro Culture)

Isolated from a patient resection. Sorted 3 times for CD24 positive cells. Determined to be a mixed tumor by qRT-PCR, FACS analysis, cell morphology and growth in animals

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

Soft Agar Growth

Soft Agar
Growth Notes

Formed colonies for 1 round but was unable to be expanded

Fibroblast qRT-PCR
C1 Corr

0.79

Fibroblast qRT-PCR
C2 Corr

0.77

Fibroblast qRT-PCR
Top Hits

COL1A1,FN1,COL1A2,VIM,COL3A1

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	Phase contrast image [20X]: cells grown on plastic as adherent monolayer
	Spheroid Culture	Phase contrast image [20X]: cells grown on plastic in StemPro media
	Xenograft from In Vitro Culture	20x image of cell culture-derived xenograft; Diagnosis confirmed

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Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.51.0

2.0.1.51.0

2.0.1.4.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.1.4.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
IDH1	p.R132G	0.6408	103	Missense_Mutation	Oncogenic	Switch-of-function	v7.1
PTCH1	p.V763Gfs*27	1.0000	111	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
TP53	p.V172D	1.0000	125	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
COL2A1	p.X236_splice	1.0000	127	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1

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