Sample Editor (PDX or In Vitro Culture)

Isolated from a patient biopsy. Sorted three separate times: the first time the cells were sorted twice for hCD90 positive cells, the second sort was twice for hCD9 and the third time the cells were sorted 3 times for hCD9. Determined to be a tumor by FACS analysis, QRT-PCR, cell morphology and positive tumorigenicity test

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

Soft Agar Growth

Soft Agar
Growth Notes

Fibroblast qRT-PCR
C1 Corr

0.70

Fibroblast qRT-PCR
C2 Corr

0.63

Fibroblast qRT-PCR
Top Hits

FN1,VIM,COL1A2,KRT5,CD45

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	20x magnification, Passage 28
	Spheroid Culture	20x magnification, Passage 17
	Xenograft from In Vitro Culture	Consistent with model

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Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.51.0

2.0.1.51.0

2.0.1.4.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.1.4.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
ARID1A	p.Q405*	0.4479	509	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
ATXN2	p.Q180Hfs*26	0.2800	25	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
ATXN2	p.Q179Afs*69	0.2800	25	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
BRAF	p.V600E	0.5938	64	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
CDK4	p.R24H	1.0000	156	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v3.14
EP400	p.Q2727Hfs*51	1.0000	81	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
EP400	p.Q2727Afs*256	0.3043	23	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
PTPRT	p.W691*	0.4031	191	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
TP53	p.C277Y	1.0000	111	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14

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