Sample Editor (PDX or In Vitro Culture)

Isolated from a resection. Sorted 3 times for hCD90 negative cells. Determined to be a tumor by FACS analysis, QRT-PCR, cell morphology and a positive tumorigenicity test

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

Soft Agar Growth

Soft Agar
Growth Notes

Fibroblast qRT-PCR
C1 Corr

0.53

Fibroblast qRT-PCR
C2 Corr

0.52

Fibroblast qRT-PCR
Top Hits

FN1,LOX,VIM,KRT5,KRT8

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	grows as large clusters 20x magnification, Passage 29
	Xenograft from In Vitro Culture	20x image of cell culture-derived xenograft

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Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.51.0

2.0.1.51.0

2.0.1.4.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.1.4.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
BCORL1	p.S1417*	1.0000	160	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
BRCA2	p.T630I	0.5546	119	Missense_Mutation	Inconclusive	Inconclusive	v3.14
EED	p.S29Qfs*10	0.0000	150	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
EED	p.N30Sfs*9	1.0000	150	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
ERBB2	p.I654V	0.3310	142	Missense_Mutation	Inconclusive	Inconclusive	v3.14
GRIN2A	p.E1176*	0.2652	230	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
KMT2B	p.R2587*	0.2879	257	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
NOTCH1	p.C74*	1.0000	173	Nonsense_Mutation	Oncogenic	Likely Loss-of-function	v3.14
RASA1	p.Q1034*	0.4719	320	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
TP53	p.R248Q	0.5027	183	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14

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