Sample Editor (PDX or In Vitro Culture)

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
ATM	p.K2811Sfs*46	0.5510	49	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
ATR	p.I774Yfs*5	0.5053	95	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
BRAF	p.V600E	0.4655	58	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
BRCA2	p.T3085Qfs*19	0.4400	100	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
CDKN1B	p.D63Rfs*62	0.4916	596	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
CREBBP	p.K1565Rfs*70	0.5559	349	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
EPHA7	p.X33_splice	0.5612	98	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v3.14
FAT1	p.X3402_splice	0.4788	165	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v3.14
FAT1	p.N126Kfs*3	0.4744	390	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
HNF1A	p.P291Qfs*51	0.4555	494	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
JAK1	p.P861Tfs*4	0.4914	291	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
KMT2C	p.K2797Rfs*26	0.9643	56	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
KMT2C	p.X338_splice	0.0693	332	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v3.14
KMT2D	p.Q2109Afs*46	0.4349	269	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
MSH3	p.K383Rfs*32	1.0000	104	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
PHOX2B	p.G268Afs*41	0.5000	234	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
PIK3R1	p.R461*	0.4394	66	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
PTCH1	p.Y1316Tfs*56	0.1209	215	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
PTEN	p.L57Wfs*42	0.5000	36	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
PTEN	p.K267Rfs*9	0.5125	80	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
RAD50	p.K722Rfs*14	0.5467	289	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
RNF43	p.G659Vfs*41	0.4644	323	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
RNF43	p.R117Pfs*8	0.9889	180	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
SESN2	p.Q229Rfs*18	0.5354	396	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
SOX9	p.510Lext49	0.4774	266	Nonstop_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
SPEN	p.A2105Lfs*33	0.4854	274	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
SPEN	p.P2461Hfs*15	0.4922	770	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
TP53	p.R273C	0.5340	103	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
FANCL	p.Q99Rfs*17	0.5088	226	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14

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