Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

134843

207-R

Value Required

W4AQF6

Disease Body Location

Head and Neck

LXSC

10023843 - Laryngeal squamous cell carcinoma

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Low grade or well differentiated	90%	5%	5%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.4.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	BRCA2	p.D1420Y	0.9444	54	Missense_Mutation	Inconclusive	Inconclusive	v3.14
	KMT2D	p.T2780Rfs*7	0.4068	413	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	NOTCH1	p.G446Afs*185	0.9952	413	Frame_Shift_Del	Oncogenic	Likely Loss-of-function	v3.14
	PBRM1	p.Q188*	1.0000	206	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	RASA1	p.Y712Ifs*14	1.0000	173	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	TP53	p.Q192*	0.9899	395	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14

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