Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

765638

272-R

Value Required

AG1

Disease Body Location

Respiratory/Thoracic

LUSC

10025126 - Squamous cell lung carcinoma

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

0

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	70%	20%	10%	<Unknown>

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.13.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.Q1303*	1.0000	128	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v3.14
	ARID1A	p.S795Tfs*38	0.1429	35	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	ARID1A	p.G797Rfs*20	0.1429	35	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	ARID1A	p.G801Vfs*14	0.1053	38	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	BLM	p.T57Hfs*4	0.5900	100	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	BRCA2	p.G602R	0.5298	151	Missense_Mutation	Inconclusive	Inconclusive	v3.14
	DTX1	p.C205Afs*101	0.1429	35	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	DTX1	p.L206Tfs*182	0.1471	34	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	DTX1	p.V208Afs*97	0.1471	34	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	NFE2L2	p.G31V	0.7216	97	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
	SESN1	p.V263Ffs*63	0.5389	167	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	SLX4	p.A376Hfs*21	0.1892	37	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	SLX4	p.L373Sfs*7	0.1667	42	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	TP53	p.X33_splice	1.0000	61	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v3.14

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