Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

116655

072-R

Value Required

AK7A17

Disease Body Location

Digestive/Gastrointestinal

MACR

10009951 - Adenocarcinoma - colon

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	80%	10%	10%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.14.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.14.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	ANKRD11	p.A2265Rfs*8	0.5000	44	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	APC	p.V452Sfs*7	0.5258	97	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	APC	p.T1556Nfs*3	0.4885	217	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	BRAF	p.V600E	0.3871	62	Missense_Mutation	Oncogenic	Gain-of-function	v3.14
	BRIP1	p.R173C	0.4466	103	Missense_Mutation	Inconclusive	Inconclusive	v3.14
	ERBB2	p.R487W	0.4778	406	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	v3.14
	FBXW7	p.R465C	0.4308	195	Missense_Mutation	Oncogenic	Loss-of-function	v3.14
	HIST1H1D	p.A186Lfs*?	0.5026	191	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	INHA	p.L189Cfs*2	0.4514	432	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	JARID2	p.R425Gfs*36	0.1385	65	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	KEAP1	p.F478Lfs*2	0.5508	236	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v3.14
	KMT2C	p.K2797Rfs*26	0.5213	188	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	KMT2D	p.T4772Nfs*9	0.2661	109	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	NOTCH3	p.K2069Rfs*16	0.5062	81	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	RAD50	p.K722Rfs*14	0.5199	277	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	RNF43	p.G659Vfs*41	0.4451	182	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	RNF43	p.P192Rfs*11	0.0000	514	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	TGFBR2	p.K153Afs*3	0.0000	354	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14
	TSC2	p.T1247Sfs*74	0.5000	126	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v3.14

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