Sample Editor (PDX or In Vitro Culture)

Isolated from pooled passage 2 PDX material. Sorted twice for hHLA positive cells. Determined to be a tumor by FACS analysis, QRT-PCR, cell morphology, and positive tumorgenicity.

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

Soft Agar Growth

Soft Agar
Growth Notes

Fibroblast qRT-PCR
C1 Corr

0.23

Fibroblast qRT-PCR
C2 Corr

0.19

Fibroblast qRT-PCR
Top Hits

KRT7,VIM,KRT18,KRT8,KRT19

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	20x magnification, Passage 25
	Xenograft from In Vitro Culture	20X image of cell culture-derived xenograft

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Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

2.0.2.51.0

2.0.2.21.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.2.21.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
BAP1	p.R385*	1.0000	190	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
CDKN2A	p.X153_splice	1.0000	55	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
NF2	p.P275Nfs*22	1.0000	128	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
SUZ12	p.L564Sfs*5	0.4761	691	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1

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