Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

625472

104-R

Value Required

H68WG3

Disease Body Location

Digestive/Gastrointestinal

COAD

10009951 - Adenocarcinoma - colon

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	80%	10%	10%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	None Found	p.W190*	0.4766	342	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.C227Mfs*21	0.5205	146	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ATRX	p.N633Tfs*16	0.4473	237	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.R1514*	0.2727	44	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	BCORL1	p.M644Hfs*21	0.5043	585	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BCORL1	p.Q798*	0.5057	441	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	BRAF	p.V600E	1.0000	62	Missense_Mutation	Oncogenic	Gain-of-function	-
	BRCA2	p.Y1220Ifs*8	0.6202	258	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	CASP8	p.R292W	0.4555	191	Missense_Mutation	Likely Oncogenic	Unknown	-
	CCND3	p.P284L	1.0000	82	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	-
	CDKN1A	p.R83Gfs*65	0.5491	224	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	CDKN2A	p.D84N	0.3846	65	Missense_Mutation	Likely Oncogenic	Loss-of-function	-
	DIS3	p.I678Ffs*59	0.3614	166	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	EPHA3	p.E647Rfs*9	0.5038	133	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ESCO2	p.T254Nfs*27	0.4663	163	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	FOXL2	p.K193Sfs*78	0.5000	142	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	INPPL1	p.R1156Gfs*46	0.5169	89	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	JARID2	p.A396Rfs*18	0.5000	204	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	KMT2A	p.K3828Rfs*31	0.5181	166	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	KMT2D	p.R5340*	0.4643	84	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	MGA	p.D2578Tfs*10	0.4545	253	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	MSH2	p.A230Lfs*16	0.4785	163	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	MSH3	p.K383Rfs*32	0.4545	77	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PIK3CA	p.C420R	0.5289	121	Missense_Mutation	Oncogenic	Gain-of-function	-
	RB1	p.R320*	0.5696	79	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	RB1	p.R418Kfs*10	0.3012	83	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	RIT1	p.A57D	0.2510	498	Missense_Mutation	Likely Oncogenic	Likely Gain-of-function	-
	RNF43	p.P660Vfs*41	1.0000	176	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	SPRTN	p.G222Afs*7	0.2571	385	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	SUZ12	p.R196Efs*4	0.5660	53	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	TET1	p.N486Ifs*6	0.5247	162	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	WT1	p.G21Rfs*31	0.1538	78	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.A3407Lfs*78	0.1731	52	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	SMARCA2	p.I1452Nfs*7	0.4118	34	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZFP36L1	p.S294Qfs*45	0.4444	54	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BRSK1	p.R379Pfs*10	0.2937	269	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	QKI	p.K134Rfs*14	0.4737	152	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-

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