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CN0330

F216

M551

Intermediate grade or moderately differentiated

80 %

5 %

15 %

1+ (Low)

Well to moderately differentiated adenocarcinoma of colon. More cribriform glands noted in the later passages, may indicate evolution of tumor. Tumor cells appear elongated, with overlapping morphology. The center of the glands consist of mucin and necrotic debris consisting of nuclear fragments ie dirty necrosis. There is occasional mitotic figures noted, indicating a highly proliferating tumor. There is also presence of stromal component, which is primarily composed of fibroblasts and some inflammatory cells. Compared to the originator samples, there is marked decrease in stromal elements.

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