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Patient ID
BL0479
Open Patient
Specimen ID
F1894
Disease Body Location
Genitourinary
OncoTree Code
BLCA
CTEP SDC Code
10044409 - Transitional cell car. - uroth.
Human Pathogen
Testing Summary
Negative
Tissue Type
Resection
Tissue Collected
Bladder
Provided Tissue Origin
Primary
Collection Date
01/0001
Age at Sampling
78
General Model Information
Model Notes
PDX Derivation/Growth:Should be QC'd regularly as tumor tends to drift towards mouse.
NGS Characterization
Able to Viably Passage
into Athymic Nude Mice?
Unknown
Mouse Strain Used
for Engraftment
NSG (NOD.Cg-Prkdc[scid]Il2rg[tm1Wjl]/SzJ)
Viable Passage
Implantation Site
Subcutaneous (flank)
MSI Status
MSI-Stable
HLA Profile(s)
A1
A2
B1
B2
C1
C2
PDX Concordance / PDM Type
A*11:01
A*26:01
B*15:01
B*27:05
C*01:02
C*03:03
7/7
PDX Metastatic in NSG?
Yes
Location of Observed Metastases
Liver, lung
Timing of Observed Metastasis
Spontaneous & Post De-bulking Metastasis
Penetrance
10% (n=81, 39d, spontaneous), 9% (n=81, 51d, de-bulking)
TCIA Imaging Data Available
No
Link to TCIA
PDX Growth Curve Data (if available)
Growth Curve Analysis
View
Passage
Growth Curve
Growth Curve Notes
0
2 of 3 models were passaged/sac'd ~61 days creating appearance of growth rate decline.
1
2
3
Export
Consensus Genomic Variants from WES Files
External Consensus Genomic Variants Data
A data file is available if a Download link is displayed:
Consensus Whole Exome Sequence (*.vcf)
Download
Ver:
2.0
Consensus Whole Exome Sequence, annotated (*.maf)
Download
Ver:
2.0
Distribution Lots
View
PDM Type
Name
Max. Passage
Cryovial for
PDX Generation
In Vitro
Culture Material
PDX
DNA Vials
PDX
RNA Vials
PDX Flash-
Frozen Vials
Organoid Culture
BL0479-F1894-V1-organoid
12
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDC: Mixed Tumor Culture
BL0479-F1894-PDC
51
Not Applicable
Available
Not Applicable
Not Applicable
Not Applicable
PDX
BL0479-F1894
5
Available
Not Applicable
Currently Unavailable
Currently Unavailable
Currently Unavailable
Export
Sample (PDX)
View
PDM Type
Sample ID
Patient/Originating
Specimen
PDX Passage
Sample Images
Avail
OncoKB Gene
Panel Data
Whole Exome
Sequence Avail
RNASeq
Avail
Organoid Culture
V1-organoid
No
Yes
Yes
Yes
Yes
PDC: Mixed Tumor Culture
PDC
No
Yes
Yes
Yes
Yes
PDX
M22
No
2
Yes
Yes
Yes
No
PDX
M22M200
No
3
Yes
No
No
Yes
PDX
M22M200M316
No
4
Yes
Yes
Yes
No
PDX
M23
No
2
Yes
Yes
Yes
Yes
PDX
M23M205
No
3
Yes
Yes
Yes
Yes
PDX
M23M205M318
No
4
Yes
Yes
Yes
Yes
PDX
M24M216
No
3
Yes
Yes
Yes
Yes
PDX
M23M207M324M413
No
5
Yes
Yes
Yes
Yes
Patient/Originator Specimen
ORIGINATOR
Yes
Yes
No
No
No
Export
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