Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

292921

168-R

Value Required

WS2

Disease Body Location

Digestive/Gastrointestinal

PAAD

10052747 - Adenocarcinoma - pancreas

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

0

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	80%	10%	10%	<Unknown>

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.E582Gfs*20	0.3209	134	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.P1594Afs*38	0.6667	414	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.K2248*	0.6177	293	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.S617Qfs*2	0.5439	57	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.R1461*	0.5412	255	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1B	p.N2124Tfs*21	0.4846	227	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID4B	p.T939Rfs*2	0.5436	241	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ASXL1	p.G646Wfs*12	0.4407	118	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	AXIN2	p.G665Afs*24	0.5041	121	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BCORL1	p.G1682Rfs*4	1.0000	39	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRCA2	p.R3384*	0.4759	187	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	CBL	p.R206*	0.5181	83	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	CD58	p.Q59Tfs*4	0.3896	77	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CIITA	p.G655Rfs*94	0.4685	111	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CTR9	p.S774Vfs*3	0.5617	162	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	DNMT3A	p.F414Lfs*7	0.4195	205	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ELF3	p.X200_splice	0.5765	85	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FAT1	p.K2139Sfs*8	0.4480	279	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	GATA3	p.S237Afs*28	0.5278	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	GNAS	p.R201H	0.4637	248	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	GPS2	p.Q290Sfs*55	0.3279	61	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.K553Nfs*52	0.4646	297	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.V788*	0.4551	156	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.G1879Vfs*16	0.4127	63	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2D	p.L2331*	0.6684	193	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KRAS	p.G12D	0.6721	183	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	MSH2	p.W345*	1.0000	144	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	PAX5	p.A322Rfs*19	0.4314	153	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTPRS	p.V1025Pfs*35	0.3298	94	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	RAD50	p.E723Gfs*5	0.3127	323	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.X2477_splice	0.5120	125	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.T305Qfs*35	0.5612	98	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SH2B3	p.A111Pfs*86	0.3056	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPEN	p.A2251Qfs*102	0.4175	206	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	STK11	p.K84del	0.5089	112	In_Frame_Del	Likely Neutral	Likely Neutral	v7.1
	TP53	p.G244C	0.4583	96	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.G654Lfs*2	0.4074	54	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.X1690_splice	0.3947	114	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZFHX3	p.R1893Gfs*35	0.4907	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARHGAP35	p.K945Rfs*3	1.0000	150	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRSK1	p.R379Pfs*54	0.4975	201	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CHD2	p.Q1392Tfs*17	0.5128	78	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZNF292	p.S1288Ffs*6	0.5256	156	Frame_Shift_Ins	Likely Oncogenic	Loss-of-function	v7.1
	ZNF292	p.S2049Vfs*11	0.5238	189	Frame_Shift_Del	Likely Oncogenic	Loss-of-function	v7.1

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