Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

292921

168-R

Value Required

WS0Y22

Disease Body Location

Digestive/Gastrointestinal

PAAD

10052747 - Adenocarcinoma - pancreas

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	55%	30%	15%	<Unknown>

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.E582Gfs*20	0.3033	122	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.P1594Afs*38	0.6556	392	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.K2248*	0.6141	241	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.S617Qfs*2	0.4815	54	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.R1461*	0.4802	252	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1B	p.N2124Tfs*21	0.5100	200	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID4B	p.T939Rfs*2	0.4958	240	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ASXL1	p.G646Wfs*12	0.4859	142	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	AXIN2	p.G665Afs*24	0.5245	143	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BCORL1	p.G1682Rfs*4	0.9512	41	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRCA2	p.R3384*	0.4730	148	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	CBL	p.R206*	0.4691	81	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	CD58	p.Q59Tfs*4	0.4512	82	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CIITA	p.G655Rfs*94	0.5462	130	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CTR9	p.S774Vfs*3	0.5427	164	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	CYLD	p.E579Kfs*5	0.5035	141	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	DNMT3A	p.F414Lfs*7	0.5223	157	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ELF3	p.X200_splice	0.4894	94	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FAT1	p.K2139Sfs*8	0.4917	301	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	GATA3	p.S237Afs*28	0.4234	111	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	GNAS	p.R201H	0.4439	223	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	KMT2B	p.K553Nfs*52	0.5287	348	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.V788*	0.5294	153	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.G1879Vfs*16	0.4304	79	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2D	p.L2331*	0.7219	187	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KRAS	p.G12D	0.6429	210	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	MSH2	p.W345*	1.0000	46	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	PAX5	p.A322Rfs*19	0.3920	125	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTPRS	p.V1025Pfs*20	0.2169	83	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	RAD50	p.E723Gfs*5	0.2230	305	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.X2477_splice	0.3802	121	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.T305Qfs*35	0.5233	86	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SH2B3	p.A111Pfs*86	0.3426	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPEN	p.A2251Qfs*102	0.5271	203	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	STK11	p.K84del	0.4173	127	In_Frame_Del	Likely Neutral	Likely Neutral	v7.1
	TP53	p.R267Q	0.5556	36	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	TP53	p.G244C	0.4615	91	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.G654Lfs*2	0.4706	85	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.X1690_splice	0.3984	128	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZFHX3	p.R1893Gfs*35	0.4615	104	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARHGAP35	p.K945Rfs*3	1.0000	159	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRSK1	p.R379Pfs*54	0.4144	222	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CHD2	p.Q1392Tfs*17	0.3425	73	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	HIRA	p.R755Kfs*67	0.4941	255	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZNF292	p.S1288Ffs*6	0.5263	133	Frame_Shift_Ins	Likely Oncogenic	Loss-of-function	v7.1
	ZNF292	p.S2049Vfs*11	0.5180	139	Frame_Shift_Del	Likely Oncogenic	Loss-of-function	v7.1

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