Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

292921

168-R

Value Required

WS1V43

Disease Body Location

Digestive/Gastrointestinal

PAAD

10052747 - Adenocarcinoma - pancreas

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	75%	%	25%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	APC	p.E582Gfs*20	0.3790	248	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.P1594Afs*38	0.6694	741	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	APC	p.K2248*	0.6824	507	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.S617Qfs*2	0.5765	85	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1A	p.R1461*	0.4705	474	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARID1B	p.N2124Tfs*21	0.4927	341	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ASXL1	p.G646Wfs*12	0.4726	201	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	AXIN2	p.G665Afs*24	0.5000	216	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BCORL1	p.P1681Qfs*20	0.9259	81	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRCA2	p.R3384*	0.5225	377	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	CD58	p.Q59Tfs*4	0.5314	175	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CIITA	p.G655Rfs*94	0.4952	208	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CTR9	p.S774Vfs*3	0.5227	331	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	DNMT3A	p.F414Lfs*7	0.4689	305	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ELF3	p.X200_splice	0.4676	139	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FANCC	p.X444_splice	0.4130	46	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FAT1	p.K2139Sfs*8	0.5767	541	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	FBXO11	p.G651*	0.9000	30	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	GATA3	p.S237Afs*28	0.4380	242	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	GNAS	p.R201H	0.5244	389	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	KMT2B	p.K553Nfs*52	0.4652	589	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.V788*	0.5455	253	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2B	p.G1879Vfs*16	0.5039	127	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2D	p.P2354Lfs*30	0.2749	251	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2D	p.L2331*	0.6222	270	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	KRAS	p.G12D	0.6432	384	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	MSH2	p.W345*	1.0000	140	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTPRS	p.V1025Pfs*35	0.3056	144	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	RAD50	p.E723Gfs*5	0.1905	630	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.X2477_splice	0.4072	194	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	SETD2	p.T305Qfs*35	0.4469	179	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SH2B3	p.A111Pfs*86	0.3310	145	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPEN	p.A2251Qfs*102	0.4626	348	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	STK11	p.K84del	0.4640	222	In_Frame_Del	Likely Neutral	Likely Neutral	v7.1
	TP53	p.R267Q	0.5588	68	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	TP53	p.G244C	0.4731	167	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.G654Lfs*2	0.4238	151	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	TSC2	p.X1690_splice	0.3947	190	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZFHX3	p.R1893Gfs*35	0.4866	187	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ARHGAP35	p.K945Rfs*3	1.0000	259	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRSK1	p.R379Pfs*54	0.8586	403	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	INTS6	p.X63_splice	0.4000	155	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	CHD2	p.Q1392Tfs*17	0.3616	177	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZNF292	p.S1288Ffs*6	0.5231	281	Frame_Shift_Ins	Likely Oncogenic	Loss-of-function	v7.1

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