Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

397859

316-R

Value Required

ORIGINATOR

Disease Body Location

Breast

IDC

10006190 - Invasive breast carcinoma

Value Required

Patient/Originator Specimen

Resection

Patient/Originating
Specimen

Passage of this Sample

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	40%	0%	60%	2+ (Moderate)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.16.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.16.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	None Found	p.P1262Hfs*16	0.1321	280	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.T1263Afs*4	0.1357	280	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.K749Yfs*4	0.0774	530	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.I751Tfs*25	0.0815	503	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.P153Sfs*84	0.1098	82	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	None Found	p.A152Mfs*12	0.1071	84	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	APC	p.N2624Gfs*21	0.1000	100	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	APC	p.T2626Ffs*13	0.0982	112	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ARID1A	p.T2060Ifs*38	0.0679	427	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ARID1A	p.Y2076Ifs*23	0.0754	464	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ARID1B	p.S40Vfs*192	0.1084	203	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ARID1B	p.S41Rfs*28	0.1073	205	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ARID1B	p.L208Hfs*22	0.2200	50	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ARID1B	p.T210Sfs*56	0.2000	50	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ARID2	p.Q1835*	0.1553	103	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	ARID4B	p.E550Gfs*6	0.0816	380	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ATP6V1B2	p.Y371F	0.1603	131	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	BCL11B	p.L370Nfs*24	0.1525	118	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BCL11B	p.E369Afs*147	0.1488	121	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.Q1248Pfs*47	0.0735	408	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.I1246Tfs*5	0.0764	419	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.D1226Efs*18	0.1013	316	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.D1226Efs*13	0.1049	305	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.D169Gfs*17	0.1149	261	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BCOR	p.A165Gfs*51	0.1221	262	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	BTG1	p.E93Rfs*9	0.1111	270	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BTG1	p.Q92Rfs*52	0.1159	276	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	CDK12	p.F1376Sfs*5	0.0917	338	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	CDK12	p.G1456Tfs*44	0.1000	240	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	CDK12	p.G1456Afs*56	0.1000	240	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	CEBPA	p.G101Rfs*6	0.1342	149	Frame_Shift_Del	Likely Oncogenic	Switch-of-function	-
	CEBPA	p.T98Afs*61	0.1402	164	Frame_Shift_Del	Likely Oncogenic	Switch-of-function	-
	DUSP4	p.A358Dfs*91	0.1746	126	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	DUSP4	p.P357Tfs*67	0.1789	123	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ETV6	p.V285Rfs*15	0.1056	606	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ETV6	p.V285Tfs*33	0.1000	600	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	FBXO11	p.L912Rfs*9	0.1184	304	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	FBXO11	p.T911Nfs*9	0.1331	323	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	FOXO1	p.P139Rfs*63	0.1376	109	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	FOXO1	p.A140Sfs*195	0.1250	104	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	KDM5C	p.T1228Lfs*71	0.1344	372	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	KDM5C	p.P1227Lfs*38	0.1316	380	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	KMT2D	p.S2312Wfs*13	0.1730	289	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	KMT2D	p.S2312Afs*11	0.1753	291	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	LATS2	p.P38Qfs*26	0.0769	286	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	LATS2	p.V34Rfs*30	0.0746	295	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	LATS2	p.V34Tfs*12	0.0759	290	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	LZTR1	p.R21Lfs*12	0.0598	468	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	MGA	p.A51*	0.1167	120	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	MGA	p.S52*	0.1034	116	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	MGA	p.A2917Gfs*7	0.0762	105	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	MGA	p.E2918Qfs*16	0.0833	108	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	MGA	-	0.1818	44	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	NSD1	p.S1937Qfs*8	0.1101	109	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	NSD1	p.K1938Afs*32	0.1009	109	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	PHF6	p.S158*	0.0809	136	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PIK3CA	p.Q546K	0.3333	189	Missense_Mutation	Oncogenic	Gain-of-function	-
	PTCH1	p.R1342Afs*30	0.0893	224	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PTCH1	p.A43Pfs*37	0.1414	99	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PTCH1	p.A42Cfs*47	0.1400	100	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PTCH1	p.G29Afs*50	0.1250	80	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PTPRD	p.D657Qfs*25	0.1233	365	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PTPRD	p.D657Lfs*32	0.1236	364	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	RB1	p.F839Sfs*10	1.0000	51	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	TP53	p.I195N	0.9917	484	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	TP53BP1	p.I738Sfs*3	0.0905	221	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	TP53BP1	p.L736Cfs*4	0.0922	217	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	TP53BP1	p.L736Vfs*5	0.0930	215	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.P3605Rfs*90	0.1529	170	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.A3604Pfs*61	0.1600	175	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.H508Rfs*9	0.1048	105	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.H508Sfs*29	0.1100	100	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.S383Rfs*71	0.1238	323	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFHX3	p.G382Vfs*15	0.1265	324	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ZNRF3	p.L26Pfs*82	0.2000	30	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZNRF3	p.R27Vfs*81	0.1562	32	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZNRF3	p.C28Sfs*79	0.1143	35	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	PPP2R2A	-	0.1556	90	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	SMARCA2	p.X1152_splice	0.2745	51	Splice_Site	Likely Oncogenic	Likely Loss-of-function	-
	ZFP36L1	p.R189Gfs*44	0.0850	200	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFP36L1	p.R172Afs*61	0.0944	392	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFP36L1	p.Q136*	0.1273	746	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	-
	HIRA	p.T666Qfs*15	0.0802	187	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	HIRA	p.T666Sfs*41	0.0838	179	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-

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