Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

997537

175-T

Value Required

HP1G72

Disease Body Location

Digestive/Gastrointestinal

COAD

10009951 - Adenocarcinoma - colon

Value Required

PDX

Tumor Biopsy

Patient/Originating
Specimen

Passage of this Sample

1

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	High grade or poorly differentiated	75%	15%	10%	2+ (Moderate)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.50.0

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download Read1 FASTQ

Download Read2 FASTQ

1.2

Download RSEM (genes)

Download RSEM (isoforms)

2.0.1.4.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	ATM	p.K2811Sfs*46	0.4839	124	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ATR	p.I774Yfs*5	0.5615	130	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	BRAF	p.V600E	0.4658	73	Missense_Mutation	Oncogenic	Gain-of-function	v7.1
	BRCA2	p.T3085Qfs*19	0.5463	205	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	CDKN1B	p.D63Rfs*62	0.6533	473	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	CREBBP	p.K1565Rfs*70	0.5367	218	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	EPHA7	p.X33_splice	0.5333	105	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FAT1	p.X3402_splice	0.5064	156	Splice_Site	Likely Oncogenic	Likely Loss-of-function	v7.1
	FAT1	p.N126Kfs*3	0.5137	438	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	HNF1A	p.P291Qfs*51	0.6732	410	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	JAK1	p.P861Tfs*4	0.4644	267	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	KMT2D	p.Q2109Afs*46	0.2731	260	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	MSH3	p.K383Rfs*32	1.0000	92	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	PHOX2B	p.G268Afs*41	0.5119	168	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	PIK3R1	p.R461*	0.6716	67	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTEN	p.L57Wfs*42	0.5536	56	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTEN	p.K267Rfs*9	0.4532	139	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	RAD50	p.K722Rfs*14	0.5350	286	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	RECQL	p.V41Sfs*2	0.3310	287	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	RNF43	p.G659Vfs*41	0.5069	217	Frame_Shift_Del	Inconclusive	Inconclusive	v7.1
	RNF43	p.R117Pfs*8	0.9876	161	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	v7.1
	SESN2	p.Q229Rfs*18	0.5110	227	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPEN	p.A2105Lfs*33	0.5297	202	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPEN	p.P2461Hfs*15	0.4672	381	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	SPRTN	p.G222Afs*7	0.4796	221	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	TP53	p.R273C	0.5747	87	Missense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZNRF3	p.L31Rfs*91	0.3438	32	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	ZNRF3	p.G612Afs*54	0.4667	405	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	FANCL	p.Q99Rfs*17	0.5033	306	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	LRP1B	p.H4368Tfs*4	0.4518	166	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	CHD4	p.K119del	0.4204	157	In_Frame_Del	Inconclusive	Inconclusive	v7.1
	CHD2	p.K1245Nfs*4	0.5138	109	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	COL2A1	p.Q36*	0.3256	43	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
	PTPN13	p.K285Nfs*45	0.5255	333	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	XRCC1	p.A189Lfs*44	0.3968	126	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	FANCE	p.P310Qfs*54	0.4176	182	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
	HOXA11	p.I299Lfs*30	0.5146	239	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1

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