Sample Editor (PDX or In Vitro Culture)

Isolated from a PDX xenograft. Sorted three times for CD24 positive cells. Determined to be a tumor by FACS analysis, QRT-PCR, cell morphology and a positive tumorigenicity test.

Tumorigenic in
NSG Mice

Spheroid Growth

Spheroid Growth
Notes

Soft Agar Growth

Soft Agar
Growth Notes

Fibroblast qRT-PCR
C1 Corr

-0.21

Fibroblast qRT-PCR
C2 Corr

-0.22

Fibroblast qRT-PCR
Top Hits

KRT5,KRT13,KRT17,CD24,KRT18

Images (if available)

In Vitro Images

View	Image Type	Notes	In Vitro Image
	Light Microscopy	20x magnification, Passage 22
	Spheroid Culture	20x magnification, Passage 22
	Xenograft from In Vitro Culture	20x image of cell culture-derived xenograft

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Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.1.51.0

2.0.1.51.0

2.0.1.4.0

Download RSEM (genes)

Download RSEM (isoforms)

Ver:

2.0.1.4.0

OncoKB Gene Panel

Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
KMT2D	p.E2081Dfs*13	0.3304	227	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
KMT2D	p.M1360Kfs*70	0.3487	238	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	v7.1
TP53	p.E204*	0.9948	387	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1
XRCC1	p.R310*	0.2256	461	Nonsense_Mutation	Likely Oncogenic	Likely Loss-of-function	v7.1

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