Sample Editor (PDX or In Vitro Culture)

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NIH, National Cancer

Institute, Division of Cancer Treatment and Diagnosis (DCTD)

Sample

116655

072-R

Value Required

AK7A15E12

Disease Body Location

Digestive/Gastrointestinal

MACR

10009951 - Adenocarcinoma - colon

Value Required

PDX

Resection

Patient/Originating
Specimen

Passage of this Sample

2

Sample
Notes

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Pathology Data (if available)

Pathology Data

View	Tumor Grade	Tumor Content	Necrosis	Stromal	Inflammatory Cells	Low Magnification Image	High Magnification Image
	Intermediate grade or moderately differentiated	80%	10%	10%	1+ (Low)

Genomic Analysis

External Genetic Analysis Data

A data file is available if a Download link is displayed:

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.51.0

Download Read1 FASTQ

Download Read2 FASTQ

2.0.2.14.0

Download RSEM (genes)

Download RSEM (isoforms)

2.0.2.14.0

OncoKB Gene Panel

View	Hugo Symbol	HGVS Protein Change	Variant Allele Frequency	Total Reads	Variant Class	Oncogenicity	Predicted Functional Effect	OncoKB Version
	None Found	p.S326Lfs*33	0.4444	81	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	ANKRD11	p.A2265Rfs*8	0.3571	28	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	APC	p.V452Sfs*7	0.4711	121	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	APC	p.T1556Nfs*3	0.5412	279	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	BRAF	p.V600E	0.5094	106	Missense_Mutation	Oncogenic	Gain-of-function	-
	FBXW7	p.R465C	0.4545	264	Missense_Mutation	Oncogenic	Loss-of-function	-
	HIST1H1D	p.A186Lfs*?	0.5308	211	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	INHA	p.L189Cfs*2	0.4820	527	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	KEAP1	p.F478Lfs*2	0.5676	296	Frame_Shift_Ins	Likely Oncogenic	Likely Loss-of-function	-
	KMT2A	p.P45Rfs*105	0.3714	35	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	KMT2D	p.R845Gfs*85	0.4706	289	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	NOTCH3	p.K2069Rfs*16	0.5147	68	Frame_Shift_Del	Likely Oncogenic	Likely Gain-of-function	-
	RAD50	p.K722Rfs*14	0.4326	319	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	RNF43	p.G659Vfs*41	0.5539	204	Frame_Shift_Del	Inconclusive	Inconclusive	-
	TSC2	p.T1247Sfs*74	0.5030	167	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ZFP36L2	p.G107Afs*80	0.5263	190	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-
	ELMSAN1	p.I659Sfs*45	0.4469	226	Frame_Shift_Del	Likely Oncogenic	Likely Loss-of-function	-

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